658395
AG 18
α-Cyano-(3,4-dihydroxy)cinnamonitrile, Tyrphostin A23, RG-50810
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
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23 Februar 2012
wird geladen
A broad-spectrum protein tyrosine kinase inhibitor. Inhibits epidermal growth factor receptor autophosphorylation (IC50 = 40 µM) and the GTPase activity of transducin (IC50 = 10 µM). Inhibits aldosterone secretion in response to Angiotensin II (Cat. No. 05-23-0101). Suppresses the activation of MAP kinases by cholecystokinin in pancreatic acini.
| Produktinformationen | |||
|---|---|---|---|
| Form | Yellow solid | ||
| Primary Target | epidermal growth factor receptor autophosphorylation | ||
| Primary Target IC50 | 40 mM | ||
| Secondary target | the GTPase activity of transducin (IC50 = 10 mM), aldosterone secretion in response to Angiotensin II | ||
| Protect from Light | Ja | ||
| Purity | ≥98% by HPLC | ||
| Chemische Formel | C10H6N2O2 | ||
| CAS-Nummer | 118409-57-7 | ||
| Lager- und Versandinformationen | |||
|---|---|---|---|
| Lagerkategorie | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
